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Establishing a preliminary quality standard for Herba Mimosae Pudicae
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Tóm tắt
Mimosa pudica L. (commonly known as “Xấu hổ” in Vietnam) is a widely used medicinal plant and serves as a raw material for various traditional medicine formulations due to its anti-rheumatic and sedative properties. However, the Vietnamese Pharmacopoeia V has not yet established a monograph specifying quality standards for this herbal material. This study aimed to develop an in-house quality standard for Herba Mimosae pudicae, including macroscopic and microscopic characterization (plant anatomy and histology); determination of moisture content; total ash; qualitative identification by thin-layer chromatography (TLC); powder microscopy analysis; acid-insoluble ash; and quantitative determination of the principal active constituent using high-performance liquid chromatography (HPLC). The medicinal material Mimosa pudica L. was characterized in terms of macroscopic and microscopic features. TLC analysis showed spots with identical color and Rf values compared to those of the reference standard. The mimosa content ranged from 264 to 364 µg/g. Quality parameters were established as follows: moisture content < 13%, foreign matter < 1%, and total ash < 8%. This study has preliminarily established a set of in-house quality standards for the medicinal plant Mimosa pudica L.
Chi tiết bài viết
Từ khóa
Mimosa pudica L., mimosine quantification, herbal material standards, HPLC analysis
Tài liệu tham khảo
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