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Date Published: 30/06/2025
Online Published: 30/06/2025
Abstract Views: 5
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Issue
Vol. 23 No. 2 (2025): Số 2 Tập 23 Năm 2025
Section
Science articles
How to Cite
Nguyen, T. H. H., Lam, T. T. L., To, L. C., Truong, M. N., Tran, Q. T., & Le, T. L. P. (2025). Comparative study on the total alkaloid content and alpha-glucosidase inhibitory activity of Tinospora Cordifolia and Tinospora crispa collected in An Giang province. Journal of Pharmacetical and Cosmetic Control, 23(2), 11-17. https://tapchikiemnghiem.vn/index.php/jpcc/article/view/55

Comparative study on the total alkaloid content and alpha-glucosidase inhibitory activity of Tinospora Cordifolia and Tinospora crispa collected in An Giang province

Thi Hong Hieu Nguyen1, Thi Thu Ly Lam1, Ly Cuong To1, Minh Nhut Truong1, Quang Tu Tran1, Thi Lan Phuong Le1,
1 Faculty of Traditional Medicine – University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

The morphological characteristics of Tinospora cordifolia and Tinospora crispa were observed and described. The stem powder of both species was analyzed for moisture content, total ash, foreign matter ratio, preliminary phytochemical analysis activity, qualitative and quantitative determination of total alkaloids by thin layer chromatography (TLC) and UV-Visible spectrophotometry method. The α-glucosidase inhibitory effect was evaluated. Research recorded morphological characteristics, moisture content, total ash, and foreign matter ratio of Tinospora cordifolia and Tinospora crispa. Quantitative analysis by spectrophotometry showed significant differences in total alkaloids between the two species. Moreover, the α-glucosidase enzyme inhibition activity of both species was potentially stronger than the positive control Acarbose, in Tinospora crispa has the strongest activity.

Article Details

Keywords

Tinospora cordifolia, Tinospora crispa, Berberin, α-glucosidase

References

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