Định lượng đồng thời adenosin và cordycepin trong một số nền mẫu thực phẩm bảo vệ sức khỏe chứa cordyceps trên thị trường Việt Nam.

Abstract

Cordyceps is a valuable medicinal mushroom genus with multiple health benefits such as improving health, strengthening the immune system, fighting cancer, or supporting the nervous system. Currently Vietnamese Pharmacopoeia does not contain any monograph on Cordyceps. Thus, it is imperative to do research on quantifying quality markers and evaluating the quality of Cordyceps and related products, contributing to post-market surveillance. Referencing to Chinese Pharmacopoeia 2020, this study developed a method to simulteneously determine adenosine and cordycepin. Using ICH and AOAC guidelines, the method was validated for sample matrices including Cordyceps and dietary supplements containing it (solid, liquid, and oily formats). Next, the method was used to analyze 26 samples including Cordyceps and dietary supplements circulated in the market with Cordyceps declarance on their labels. The results show that these products contain adenosine and cordycepin but at various levels.